Structural basis for sensory rhodopsin function
نویسندگان
چکیده
منابع مشابه
Structural basis for sensory rhodopsin function.
The crystal structure of sensory rhodopsin II from Natronobacterium pharaonis was recently solved at 2.1 A resolution from lipidic cubic phase-grown crystals. A critical analysis of previous structure-function studies is possible within the framework of the high-resolution structure of this photoreceptor. Based on the structure, a molecular understanding emerges of the efficiency and selectivit...
متن کاملRhodopsin: structural basis of molecular physiology.
The crystal structure of rod cell visual pigment rhodopsin was recently solved at 2.8-A resolution. A critical evaluation of a decade of structure-function studies is now possible. It is also possible to begin to explain the structural basis for several unique physiological properties of the vertebrate visual system, including extremely low dark noise levels as well as high gain and color detec...
متن کاملStructural basis for cardiac function.
ARMOUR, J. A., AND W. C. RANDALL. Structural basis for cardiac function. Am. J. Physiol. 218(6): 1517-1523. 1970.-In nine species of,mammals, anatomic evaluation of fresh specimens demonstrated that the ventricles of the heart are grossly structured as a continuum of muscle strands. These strands originate and insert into a basal fibrous skeleton consisting of four interconnected, triangular ac...
متن کاملPhotoreactions and Structural Changes of Anabaena Sensory Rhodopsin
Anabaena sensory rhodopsin (ASR) is an archaeal-type rhodopsin found in eubacteria. The gene encoding ASR forms a single operon with ASRT (ASR transducer) which is a 14 kDa soluble protein, suggesting that ASR functions as a photochromic sensor by activating the soluble transducer. This article reviews the detailed photoreaction processes of ASR, which were studied by low-temperature Fourier-tr...
متن کاملActive state of sensory rhodopsin II: structural determinants for signal transfer and proton pumping.
The molecular mechanism of transmembrane signal transduction is still a pertinent question in cellular biology. Generally, a receptor can transfer an external signal via its cytoplasmic surface, as found for G-protein-coupled receptors such as rhodopsin, or via the membrane domain, such as that in sensory rhodopsin II (SRII) in complex with its transducer, HtrII. In the absence of HtrII, SRII f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 2002
ISSN: 0005-2736
DOI: 10.1016/s0005-2736(02)00569-2